Open AccessStructures of kinesin motor proteins
Author(s) -
Marx Alexander,
Hoenger Andreas,
Mandelkow Eckhard
Publication year - 2009
Publication title -
cell motility and the cytoskeleton
Language(s) - English
Resource type - Journals
eISSN - 1097-0169
pISSN - 0886-1544
DOI - 10.1002/cm.20392
Subject(s) - kinesin , microtubule , biology , motor protein , cytoskeleton , microbiology and biotechnology , molecular motor , microtubule associated protein , cell , biochemistry
Abstract Almost 25 years of kinesin research have led to the accumulation of a large body of knowledge about this widespread superfamily of motor and nonmotor proteins present in all eukaryotic cells. This review covers developments in kinesin research with an emphasis on structural aspects obtained by X‐ray crystallography and cryoelectron microscopy 3‐D analysis on kinesin motor domains complexed to microtubules. Cell Motil. Cytoskeleton 66: 958–966, 2009. © 2009 Wiley‐Liss, Inc.