Open AccessAvailable and affordable complementary treatments for COVID‐19: From hypothesis to pilot studies and the need for implementation
Author(s) -
Bousquet Jean,
Haahtela Tari,
Blain Hubert,
Czarlewski Wienczyslawa,
Zuberbier Torsten,
Bedbrook Anna,
Cruz Alvaro A.,
Fonseca Joao A.,
Klimek Ludger,
Kuna Piotr,
Samolinski Boleslaw,
Valiulis Arunas,
Lemaire Antoine,
Anto Josep M.
Publication year - 2022
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1002/clt2.12127
Subject(s) - medicine , covid-19 , curcumin , clinical trial , placebo , pharmacology , alternative medicine , disease , intensive care medicine , infectious disease (medical specialty) , outbreak , virology , pathology
Vaccination is a highly effective preventive measure against COVID‐19. However, complementary treatments are needed to better control the disease. Fermented vegetables and spices, agonists of the antioxidant transcription factor nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) and TRPA1/V1 channels (Transient Receptor Potential Ankyrin 1 and Vanillin 1), may help in the control of COVID‐19. Some preliminary clinical trials suggest that curcumin (spice) can prevent some of the COVID‐19 symptoms. Before any conclusion can be drawn and these treatments recommended for COVID‐19, the data warrant confirmation. In particular, the benefits of the foods need to be assessed in more patients, through research studies and large trials employing a double‐blind, placebo‐controlled design.