A case report of simultaneous thrombosis of two coronary artery stents in association with clopidogrel resistance | Zendy

Lee Jin Sun | Zendy; Dunn Steven P. | Zendy; Marshall Helen M. | Zendy; Cohen Mauricio G. | Zendy; Smyth Susan S. | Zendy

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A case report of simultaneous thrombosis of two coronary artery stents in association with clopidogrel resistance

Author(s) -

Lee Jin Sun,

Dunn Steven P.,

Marshall Helen M.,

Cohen Mauricio G.,

Smyth Susan S.

Publication year - 2007

Publication title -

clinical cardiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.263

H-Index - 72

eISSN - 1932-8737

pISSN - 0160-9289

DOI - 10.1002/clc.9

Subject(s) - medicine , clopidogrel , conventional pci , cardiology , thrombosis , antiplatelet drug , incidence (geometry) , platelet , artery , stent , aspirin , myocardial infarction , optics , physics

Despite aggressive antiplatelet therapy in the setting of PCI, the incidence of acute stent thrombosis remains approximately 0.5–2%. We report a patient with simultaneous thrombosis of two drug‐eluting coronary artery stents, suggesting a systemic thrombotic state. Evaluation by optical platelet aggregometry revealed clopidogrel resistance, which was overcome at a higher drug dose. We aim to highlight the potential utility of platelet function analysis to guide therapy for patients in whom inadequate antiplatelet therapy may have catastrophic clinical outcomes. Copyright © 2007 Wiley Periodicals, Inc.

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