Open AccessShould standard medical therapy for angina include a statin?
Author(s) -
Corti Roberto,
Fuster Valentin
Publication year - 2004
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960271020
Subject(s) - medicine , statin , angina , guideline , cardiology , coronary artery disease , coronary heart disease , cholesterol , medical therapy , myocardial infarction , pathology
Although a wealth of evidence supports the use of 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase inhibitors (statins) in patients with clinically evident coronary artery disease, these agents are still underutilized. Statins are the most effective agents in reducing low‐density lipoprotein‐cholesterol among lipid‐lowering drugs, and studies have recently shown that they improve endothelial function and plaque stabilization, and induce regression of atherosclerotic lesions. This article reviews the most recent evidence and guideline recommendations supporting the use of statins in chronic stable angina pectoris and acute coronary syndromes.