Open AccessDetection of patients with hypertrophic cardiomyopathy at risk for paroxysmal atrial fibrillation during sinus rhythm by P‐wave dispersion
Author(s) -
Köse Sedat,
Aytemir Kudret,
Sade Elif,
Can Ilknur,
Özer Necla,
Amasyali Basri,
Aksöyek Serdar,
Övünç Kenan,
Özmen Ferhan,
Atalar Enver,
Işik Ersoy,
Kes Sirri,
Demirtaş Ertan,
Oto Ali
Publication year - 2003
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960260910
Subject(s) - medicine , hypertrophic cardiomyopathy , paroxysmal atrial fibrillation , cardiology , sinus rhythm , atrial fibrillation , normal sinus rhythm , rhythm , sinus (botany) , cardiomyopathy , heart failure , botany , biology , genus
Background : Paroxysmal atrial fibrillation (PAF) in hypertrophic cardiomyopathy (HCM) is associated with poor prognosis. Previous studies have shown good correlation between P‐wave dispersion (Pd) and occurrence of PAF. However, Pd in patients with HCM for predicting PAF has not been studied. Hypothesis : The aim of the study was to determine whether Pd could identify patients with HCM who are likely to suffer from PAF. Methods : Twenty‐two patients with HCM with a history of PAF (Group 1) and 26 patients with HCM without a history of PAF (Group 2) were studied. Maximum (Pmax) and minimum (Pmin) P‐wave durations, as well as P‐wave dispersion (Pd = Pmax‐Pmin) were calculated from 12‐lead surface electrocardiograms (ECG). Results : P‐wave dispersion was significantly different between the groups (Group 1:55 ± 6 msvs. Group 2:37 ± 8 ms; p<0.001), while Pmax (Group 1: 134 ± 11 ms vs. Group 2: 128 ± 13 ms; p = 0.06) and Pmin (Group 1: 78 ± 9 ms vs. Group 2: 81 ± 7 ms; p = 0.07) was not significantly different. Patients with a history of PAF had higher left atrial diameter than the patients without PAF (Group 1:52 ± 8 mm vs. Group 2:48 ± 10 mm; p = 0.02). A cut‐off value of 46 ms for Pd had a sensitivity of 76% and a specificity of 82% in discriminating between patients with and without PAF. Conclusion : This study suggests that P‐wave dispersion could identify patients withHCM who are likely to develop PAF.