Open AccessGenetic markers for coronary heart disease
Author(s) -
Breslow Jan L.
Publication year - 2001
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960240706
Subject(s) - medicine , cholesterylester transfer protein , apolipoprotein b , homocysteine , coronary heart disease , lipoprotein , cholesterol , lipoprotein lipase , genetic variation , high density lipoprotein , lipoprotein(a) , cardiology , environmental health , population , adipose tissue
Coronary heart disease (CHD) is a complex disease that is affected by environmental as well as genetic factors. Research is ongoing that probes the relationship of human genetic variation to disease, potentially leading to better diagnosis and therapy. Variation in factors such as low‐density lipoprotein cholesterol, apolipoprotein E, high‐density lipoprotein cholesterol, apolipoprotein A‐I/CIII/A‐IV, lipoprotein lipase, cholesteryl ester transfer protein, lipoprotein (a), and homocysteine may affect CHD risk via genetic or environmental mechanisms or their interactions.