Open Accesshistamine—can it cause an acute coronary event?
Author(s) -
Gupta Mahendra Kumar,
Gupta Parul,
Rezai Feridoun
Publication year - 2001
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960240317
Subject(s) - medicine , histamine , myocardial infarction , chest pain , cardiology , coronary artery disease , myocardial ischaemia , ischemia , artery
Myocardial infarction (MI) occurring during the course of an allergic urticarial reaction in the absence of systemic hypotension has been rarely reported. This paper reports the case of a 28‐year‐old woman with no significant risk factors for coronary artery disease who presented with generalized urticaria associated with chest pain and had electrocardiographic and enzymatic evidence of an acute MI. Review of the literature suggests that local histamine release may induce spasm of the coronary vasculature, thus leading to myocardial ischemia and infarction.