Open AccessNonpharmacologic treatment of hypertriglyceridemia: Focus on fish oils
Author(s) -
Harris William S.
Publication year - 1999
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960221408
Subject(s) - medicine , fish oil , hypertriglyceridemia , incidence (geometry) , triglyceride , coronary artery disease , fish <actinopterygii> , physiology , cardiology , cholesterol , fishery , physics , optics , biology
Abstract Early studies in Greenland Eskimos stimulated interest in evaluating the effect of Omega‐3 fatty acids on coronary artery disease. Subsequent studies showed a significant decrease in triglyceride levels in patients receiving high doses of fish oil containing DHA and EPA. Slight increases in LDL were also observed in patients receiving fish oil supplements. These studies have also shown a dose—response effect which persists as long as supplementation continues. Later trials, specifically the Diet and Reinfarction Trial and the Indian Experiment of Infarct Survival, have demonstrated a reduction in cardiac death rates and in the incidence of cardiac symptoms in patients receiving fish oil.