Open AccessAngiotensin‐Converting enzyme inhibitor‐induced pancreatitis
Author(s) -
Muchnick J. S.,
Mehta J. L.
Publication year - 1999
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960220117
Subject(s) - medicine , benazepril , pancreatitis , angiotensin converting enzyme , ace inhibitor , pancreatic disease , gastroenterology , endocrinology , pancreas , blood pressure
Approximately 2% of pancreatitis in adults is drug induced. Although some angiotensin‐converting enzyme (ACE) inhibitors have been associated with pancreatitis, to the knowledge of the authors this is the first reported case involving benazepril. This case report presents laboratory‐ and image‐proven pancreatitis in a noninsulin dependent 70‐year‐old man. The patient took benazepril at three different times and experienced the same epigastric symptoms 30 min after each dose. Possible mechanisms are reviewed. Clinicians should strongly consider discontinuing ACE inhibitors, including benazepril, in patients with pancreatitis of no identifiable source.