Open AccessDoxorubicin‐induced cardiomyopathy treated with carvedilol
Author(s) -
Fazio Serafino,
Palmieri Emiliano Antonio,
Ferravante Beatrice,
Bon È Filomena,
Biondi Bernadette
Publication year - 1998
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960211017
Subject(s) - medicine , carvedilol , cardiomyopathy , doxorubicin , cardiology , heart failure , chemotherapy
Even today, heart failure due to doxorubicin‐induced dilated cardiomyopathy seems to have a poor prognosis, as it is often irreversible and relatively unresponsive to standard medical treatment. This paper describes the first case of a patient complaining of severe symptoms of congestive heart failure due to doxorubicin‐induced dilated cardiomyopathy unresponsive to standard medical treatment (digoxin, diuretics, and angiotensin‐converting enzyme inhibitor), who showed complete clinical recovery and significant improvement of left ventricular dysfunction after carvedilol treatment. It also illustrates the possibility that carvedilol may be a first‐choice drug for the treatment of this disease.