Open AccessMonocyte‐endothelial cell interaction in atherogenesis and thrombosis
Author(s) -
Ikeda Uichi,
Takahashi Masafumi,
Shimada Kazuyuki
Publication year - 1998
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960210103
Subject(s) - medicine , cell adhesion molecule , coagulation , monocyte , endothelial stem cell , endothelium , soluble cell adhesion molecules , thrombosis , cell–cell interaction , immunology , cell adhesion , matrix metalloproteinase , microbiology and biotechnology , cell , tissue factor , in vitro , biology , biochemistry
Cellular interactions between leukocytes and the endothelium are critical events in vascular biology, such as atherosclerosis and acute coronary syndrome. When monocytes and endothelial cells are activated via direct cell‐cell interaction, both types of cells express several biologically active molecules such as adhesion molecules, cytokines, coagulation and fibrinolytic factors, metalloproteinases, and vasoactive substances. All of these molecules could contribute to atherogenesis and thrombosis.