Dobutamine‐induced transmural myocardial ischemia in a patient with mild coronary lesions | Zendy

Kardaras Fotis G. | Zendy; Bonou Maria S. | Zendy; Kardara Dimitra F. | Zendy; Kranidis Athanasios I. | Zendy; Sioras Elias P. | Zendy; Anthopoulos Lambros P. | Zendy

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Dobutamine‐induced transmural myocardial ischemia in a patient with mild coronary lesions

Author(s) -

Kardaras Fotis G.,

Bonou Maria S.,

Kardara Dimitra F.,

Kranidis Athanasios I.,

Sioras Elias P.,

Anthopoulos Lambros P.

Publication year - 1996

Publication title -

clinical cardiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.263

H-Index - 72

eISSN - 1932-8737

pISSN - 0160-9289

DOI - 10.1002/clc.4960190214

Subject(s) - medicine , dobutamine , cardiology , hypokinesia , ischemia , angina , coronary artery disease , chest pain , stenosis , artery , myocardial ischemia , hemodynamics , myocardial infarction

A 70‐year‐old man was admitted for evaluation of retrosternal pain at rest. During infusion of dobutamine (25 μg/kg/min) the patient developed angina, ST‐segment elevation in the inferior leads, and echocardiographic hypokinesia in the inferior‐basal myocardial wall. Coronary angiography revealed insignificant (20‐30%) stenosis of the right coronary artery and a normal remaining tree. This case suggests that dobutamine may induce transmural myocardial ischemia in patients with mild coronary lesions, probably by producing occlusive coronary spasm on a substrate of arterial endothelial dysfunction.

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