Open AccessPharmacological management of acute myocardial infarction
Author(s) -
Jain Praveer,
Vlay Stephen C.
Publication year - 1992
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960151103
Subject(s) - medicine , myocardial infarction , aspirin , intensive care medicine , cardiology
The routine medical management of patients with acute myocardial infarction (AMI) has undergone major changes in the last decade. Several large‐scale trials have firmly established the effectiveness of thrombolytic therapy, beta blockers, and aspirin in the treatment of AMI. The critical issues include reducing myocardial oxygen demand and restoring adequate blood supply to the ischemic regions of the myocardium. As a result, the ability to intervence in patients with AMI has improved significantly. The purpose of this review is to discuss briefly the results of major trials of primary and secondary pharmacological intervention which had a direct impact on the care of patients with AMI. It concludes with current recommendations for the management of patients with AMI.