Open AccessNoninvasive evaluation of left ventricular performance by the shortest distance between mitral leaflets coaptation and interventricular septum at end‐systole
Author(s) -
Ohte Nobuyuki,
Narita Hitomi,
Hashimoto Takeshi,
Takase Rie,
Kobayashi Kenji,
Akita Sachie,
Fujinami Takao
Publication year - 1992
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960150908
Subject(s) - medicine , cardiology , ejection fraction , interventricular septum , systole , parasternal line , mitral regurgitation , end systolic volume , diastole , coronary artery disease , mitral valve , stroke volume , heart failure , ventricle , blood pressure
We attempted to evaluate left ventricular performance from the shortest distance between the mitral leaflets coaptation and the interventricular septum at endsystole (MVC‐IVS distance). The subjects were 37 patients with coronary artery disease (CAD) with prior myocardial infarction (MI), 8 with CAD without prior MI, 22 with atypical chest pain, and 4 with aortic regurgitation. The MVC‐IVS distance was measured on a two‐dimensional echocardiogram obtained from the parasternal or apical long‐axis view and frozen at end‐systole. Left ventricular end‐systolic volume and end‐diastolic volume were obtained by left ventriculography, and the left ventricular ejection fraction was calculated. A significant positive correlation was observed between the MVC‐IVS distance and the end‐systolic volume (r=0.83, p<0.001); a close correlation was found between the left ventricular end‐systolic volume and ejection fraction by monoexponential fitting (r= –0.91, p<0.001). Thus, a significant negative correlation was observed between the MVC‐IVS distance and the left ventricular ejection fraction (LVEF) (r= –0.83, p<0.001). An MVC‐IVS distance of 30 mm suggests diagnosis of left ventricular dysfunction (LVEF < 50%) with high sensitivity (94.4%) and specificity (90.6%), while a value <30 mm suggests that the left ventricular performance is likely to be normal. Thus one can easily evaluate the left ventricular performance noninvasively using this new index.