Open AccessHemofiltration as treatment for patients with refractory heart failure
Author(s) -
Inoue Teruo,
Sakai Yoshihiko,
Morooka Shigenori,
Takayanagi Kan,
Hayashi Terumi,
Takabatake Yutaka
Publication year - 1992
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960150708
Subject(s) - medicine , hemofiltration , oliguria , cardiogenic shock , heart failure , cardiology , pulmonary wedge pressure , central venous pressure , blood pressure , hemodynamics , anesthesia , hemodialysis , renal function , myocardial infarction , heart rate
Hemofiltration was performed in 15 patients with refractory congestive heart failure. All of these patients had oliguria, although intensive treatment with diuretics, digitalis, vasodilators, and catecholamines was prescribed. Hemofiltration was performed under hemodynamic monitoring in 14 patients. The water removal by hemofiltration decreased pulmonary arterial pressure, pulmonary capillary wedge pressure and right atrial pressure. Despite these hemodynamic improvements, nine patients (60%) died within one month after the start of hemofiltration; the causes were fatal arrhythmia in three, renal failure in two, sepsis in one and irreversible cardiogenic shock in three. Oliguria for over 15 h or a serum creatinine concentration of more than 4.0 mg/dl at the start of hemofiltration related to poor prognosis. In view of these results, hemofiltration for refractory heart failure should be started earlier and performed carefully in order to avoid arrhythmia, cardiogenic shock, and other complications.