
Effects of atrioventricular block on ventricular fibrillation threshold in dog
Author(s) -
Kumagai Koichiro,
Tashiro Eiichiro,
Moroe Kazuo,
Hiroki Tadayuki,
Arakawa Kikuo
Publication year - 1991
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960140710
Subject(s) - medicine , atrioventricular block , ventricular fibrillation , cardiology , heart block , electrocardiography
The effects of complete atrioventricular block (CAVB) on ventricular vulnerability were studied 1 week after a transcatheter electrical ablation of the AV junction in 18 closed‐chest dogs. All dogs exhibited CAVB and a stable ventricular escape rhythm with a mean cycle length of 1795±600 ms. Although QT interval during CAVB was significantly prolonged compared with that during the sinus rhythm, QTc interval was significantly shortened. The ventricular fibrillation threshold was significantly elevated after creation of the block (from 9.35±2.28 to 12.3±3.69 mA, p < 0.01). Thus, CAVB which is not associated with QTc prolongation would be even less likely to play an important role in producing ventricular fibrillation presumably including torsades de pointes or polymorphous ventricular tachycardia.