Open AccessImmunologic Basis of Cardiovascular Disease: An overview
Author(s) -
Pober Jordan S.
Publication year - 1991
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960140601
Subject(s) - medicine , disease , pathogenesis , transplantation , kawasaki disease , immunology , immune system , intensive care medicine , pathology , cardiology , artery
Summary : Recent investigations suggest that the immune system plays a major role in the pathogenesis of two distinct forms of cardiovascular disease, Kawasaki disease (KD) and graft “atherosclerosis,” following cardiac transplantation. However, the precise immunologic mechanisms that lead to vessel injury in these two clinical entities are as yet undefined. The purpose of this symposium was to review some of the more important ongoing investigations in both fields.