Open AccessDiurnal change of giant negative T wave in patients with hypertrophic cardiomyopathy
Author(s) -
Iida K.,
Sugishita Y.,
Yukisada K.,
Ito I.
Publication year - 1990
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960130408
Subject(s) - medicine , hypertrophic cardiomyopathy , cardiology , atropine , electrocardiography , ambulatory , cardiomyopathy , t wave , heart failure
To examine the diurnal change of negative T wave (deeper than 10 mm in precordial leads) in apical hypertrophic cardiomyopathy and the mechanism of giant negative T wave, 24‐h ambulatory electrocardiographic monitoring was performed in 8 patients with apical hypertrophic cardiomyopathy, and effect of atropine on electrocardiogram was studied. The mean depth of negative T wave at 1, 2, and 3 P. M. was 9.3±3.0 mm, and that at 1, 2, and 3 A. M. was 12.6 ± 4.8 mm. The mean R‐R interval at 1, 2, and 3 P. M. was 792 ± 113 ms and that at 1, 2, and 3 A. M. was 1055 ± 94 ms. In seven patients (88%), negative T wave was deeper during the night than during the daytime. There was a positive correlation between R‐R interval and depth of negative T wave in 6 patients (75%). Despite significant shortening of R‐R interval (879 ± 116 to 804 ± 110 ms, p < 0.05), atropine did not significantly change the depth of negative T wave (14 ± 5 to 14 ± 5 mm). In conclusion, negative T wave is not fixed, but is variable, diumally, probably due to the change of sympathetic tone.