Open AccessBiphasic response of coronary arterial diameter to intracoronary ergonovine
Author(s) -
Mohri M.,
Okamatsu S.,
Nakamura M.
Publication year - 1988
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960111011
Subject(s) - ergonovine , medicine , cardiology , artery , constriction , myocardial infarction , angina
This report presents a case of paradoxical coronary arterial dilation induced by intracoronary ergonovine. When compared with the control angiogram, the right coronary artery obviously dilated with selective, intracoronary administration of cumulative doses of 5 μg and 15 μg ergonovine without concomitant hemodynamic changes. Additional intracoronary infusion of 35 μg ergonovine into the right coronary artery inversely increased vascular tone of the vessel associated with a focal hyper‐constriction. Such a biphasic response of arterial diameter to intracoronary ergonovine was also observed in the left coronary artery, but the degree of dilation was much smaller.