Open AccessPrognostic significance of 24‐hour ambulatory electrocardiographic monitoring in patients with dilative cardiomyopathy: A prospective study
Author(s) -
Ikegawa T.,
Chino M.,
Hasegawa H.,
Usuba F.,
Suzuki S.,
Ookura M.,
Nishikawa K.
Publication year - 1987
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960100202
Subject(s) - medicine , cardiology , sudden death , cardiomyopathy , sudden cardiac death , ambulatory , ventricular tachycardia , logistic regression , univariate analysis , multivariate analysis , heart failure
We studied 33 patients with dilative cardiomyopathy to evaluate the predicting factors for sudden death occurring within one year. The information on each of the patients included history, physical examinations, two‐dimensional echocardiograms, 24‐h ambulatory electrocardiograms, and cardiac catheterization or autopsy. Patients were followed up for one year. Univariate analysis showed maximum number of premature ventricular complexes per hour (PVCs/h)(p= .0012), maximum beats per episode of ventricular tachycardia (VTmax) (p=.0012), and left ventricular end‐diastolic pressure (p=.046) to be significant prognostic risk indicators of sudden death within one year. To select the best combination of factors that predict sudden death, multivariate stepwise logistic regression analysis was performed. By this method, only PVCs/h and VTmax were selected as the best combination. Probability of sudden cardiac death was 80% in patients showing both frequent (> 100/h) PVCs and presence of VT (VTmax≤3), and 6% in patients with neither or both. We concluded that PVCs/h and VTmax are independent and significant prognostic factors in patients with dilative cardiomyopathy.