Open AccessMitral valve prolapse in the ventriculogram: Scintigraphic, electrocardiographic, and hemodynamic abnormalities
Author(s) -
Tebbe U.,
Schicha H.,
Neumann P.,
Voth E.,
Emrich D.,
Neuhaus K.L.,
Kreuzer H.
Publication year - 1985
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960080607
Subject(s) - medicine , hemodynamics , cardiology , mitral valve prolapse , mitral valve
Patients with mitral valve prolapse (MVP) frequently have chest pain, which may be difficult to differentiate from angina pectoris in coronary artery disease (CAD). We performed resting and exercise ECGs, pulmonary arterial pressure measurements, radionuclide ven‐triculography ( 99m mtechnetium), and perfusion scintigrams (20lthallium) in 56 patients with angiographically proven MVP and no CAD. Pathological results were obtained in 31% of exercise ECGs, 33% of pulmonary arterial pressure measurements during exercise, 22% of radionuclide ventriculographies, and in 75% of thallium perfusion scintigrams. A significant correlation in pathological results was found only between exercise ECG and both radionuclide ventriculography and pulmonary arterial pressure measurements. Because of the high prevalence of falsepositive perfusion scintigrams in patients with typical or atypical chest pain, the use of exercise 2 T1 imaging as a screening method to separate patients with MVP from those with CAD will not be appropriate. The variability of cardiac abnormalities in our patients with MVP and angiographically normal coronary arteries suggests that the MVP syndrome may represent a variable combination of metabolic, ischemic, or myopathic disorders.