Open AccessSuperiority of supine bicycle over isometric handgrip exercise in the assessment of ischemic heart disease: An evaluation of left ventricular ejection fraction response using radionuclide angiography
Author(s) -
Kaul S.,
Hecht H. S.,
Hopkins J.,
Siedman R. I.,
Singh B. N.
Publication year - 1984
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960071006
Subject(s) - isometric exercise , medicine , supine position , ejection fraction , cardiology , radionuclide angiography , coronary artery disease , heart failure
Left ventricular ejection fraction (LVEF) response to supine bicycle and isometric handgrip exercise was evaluated in 15 patients with documented coronary artery disease (CAD) and stress‐induced ischemia using radionuclide angiography. For purposes of analysis, the patients were divided into two groups: group I (n=7) with single‐vessel disease and group II (n = 8) with multiple‐vessel disease including 3 with left main artery disease. The studies were repeated 18 days later at similar external workloads to assess reproducibility of both tests. LVEF response to bicycle exercise was different for the two groups. The change in LVEF from rest to peak exercise was +0.04±0.02 for group I and ‐0.07±0.04 for group II (p <.001). LVEP response to isometric handgrip exercise was not different between the two groups. The change from rest to end of handgrip exercise was ‐0.02+0.02 for group I and ‐0.05 ±0.02 for group II. The reproducibility of LVEF response to bicycle exercise at similar workloads on day 1 and day 19 was good (r=0.85) while it was poor for isometric handgrip testing (r=0.67). Our data demonstrate that radionuclide angio‐graphic measurement of LVEF response to supine bicycle exercise testing is superior to LVEF response to isometric handgrip testing in the evaluation of patients with CAD.