Open AccessUnloading the right ventricle in the crest syndrome variant of progressive systemic sclerosis (scleroderma)
Author(s) -
Morrison D.,
Goldman S.,
Alepa F. P.
Publication year - 1984
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960070111
Subject(s) - medicine , crest syndrome , scleroderma (fungus) , progressive systemic sclerosis , systemic scleroderma , ventricle , crest , systemic disease , cardiology , connective tissue disease , pathology , immunopathology , raynaud disease , autoimmune disease , disease , inoculation , physics , quantum mechanics
A patient with severe pulmonary hypertension secondary to the CREST syndrome variant of scleroderma is described. Acute reductions in both pulmonary artery pressure and total pulmonary resistance were seen with nifedipine and oxygen administration. Reductions in resistance were maintained for over one month with this combination. These results raise the possibility that some of the pulmonary hypertension seen in this condition is reversible.