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Coronary spasm associated with urticaria: Report of a case mimicking anaphylaxis
Author(s) -
Bristow M. R.,
Ginsburg R.,
Kantrowitz N. E.,
Baim D.S.,
Rosenbaum J. T.
Publication year - 1982
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960050307
Subject(s) - medicine , anaphylaxis , vasoactive , histamine , kounis syndrome , coronary vasospasm , ergonovine , artery , cardiology , platelet aggregation , thromboxane a2 , allergy , aspirin , anesthesia , platelet , myocardial infarction , coronary angiography , angina , immunology
Recent investigations suggest that the vasoactive substances, histamine, prostaglandin E 2 , and thromboxane A 2 are mediators of coronary artery spasm. These substances may be released during an episode of urticaria. We report here a case of coronary artery spasm associated with an episode of acute urticaria. The coronary spasm may have been mediated by the vasoactive substances released from basophils and secondary platelet aggregation, known to occur with urticaria.

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