Open AccessDPTI/STTI—An index of the myocardial oxygen supply/demand ratio?
Author(s) -
Baller D.,
Zipfel J.,
Hellige G.
Publication year - 1980
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.4960030208
Subject(s) - medicine , cardiology , index (typography) , myocardial ischemia , ischemia , diastole , oxygen , vasodilation , anesthesia , blood pressure , chemistry , organic chemistry , world wide web , computer science
The DPTI/STTI (diastolic pressure‐time index/tension‐time index) ratio is applied as an indicator of myocardial ischemia particularly in cardiovascular and anesthesiologic care units. The validity of the DPTI/STTI ratio was examined in intact dogs with large variations of oxygen supply and demand. The correlation of DPTI/STTI to the directly measured oxygen supply/demand ratio was poor even under maximal coronary vasodilatation. Many data points were far below the critical DPTI/STTI values (reported previously) without occurrence of myocardial ischemia, failure, or edema. Therefore caution is necessary if the DPTI/STTI ratio is to be applied to humans.