Open AccessTen‐year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion
Author(s) -
Kim Yong Kyun,
Jang Chae Won,
Kwon Soon Ho,
Kim Jae Hoon,
Lerman Amir,
Bae JangHo
Publication year - 2021
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.23668
Subject(s) - medicine , mace , culprit , myocardial infarction , ejection fraction , cardiology , lesion , stenosis , percutaneous coronary intervention , artery , surgery , heart failure
Background We assessed the long‐term clinical outcomes of an intermediate lesion (IL) according to the presence of a combined culprit lesion (CCL). Hypothesis Long‐term clinical outcomes of IL may be affected by the presence of a CCL. Methods Angiographic findings ( n = 1096) and medical chart were reviewed. Patients with IL were divided into two groups: IL without CCL group ( n = 383, 64.5%) and IL with CCL group ( n = 211, 35.5%). Results The major adverse cardiovascular events (MACE) in the IL with CCL group were significantly higher than those in the IL without CCL group (death: 12.3% vs. 7.0%, myocardial infarction: 3.3%vs. 0.5%, stroke: 6.6% vs. 2.6%, and revascularization [RVSC]: 25.1% vs. 7.6%) during a mean follow up period of 118.4 ± 5.5 months. IL related RVSC rate in the IL with CCL group was higher than that in the IL without CCL group (5.7% vs. 2.1%, p = 0.020). RVSC rate related to IL in total subjects was lower than that related to stented lesion (3.4% vs. 6.4%). The important predictors of total MACE in total subjects were the presence of CCL, IL percent diameter stenosis, hypertension, history of percutaneous coronary intervention, blood glucose and ejection fraction. The predictors of IL related RVSC were IL percent diameter stenosis and IL located in the right coronary artery. Conclusion 10‐year clinical outcomes of an IL (especially IL without CCL) were better than those of stented lesions. This study suggests that the IL can be safely followed up in sites that do not have ability to assess functional study.