Open AccessRisk of atrial fibrillation in patients with pneumoconiosis: A nationwide study in Taiwan
Author(s) -
Hu WeiSyun,
Lin ChengLi
Publication year - 2020
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.23290
Subject(s) - medicine , pneumoconiosis , atrial fibrillation , hazard ratio , proportional hazards model , comorbidity , incidence (geometry) , cohort , cohort study , cardiology , confidence interval , pathology , physics , optics
Background To investigate the incidence of new‐onset atrial fibrillation (AF) among subjects with pneumoconiosis using the Taiwan National Health Insurance Research Database. Hypothesis Pneumoconiosis patients are at an increased risk of AF. Methods A total of 12 209 pneumoconiosis patients were in the exposure cohort. Patients without pneumoconiosis were included as the comparison cohort. Both cohorts were matched by gender, age, comorbidity, and index year in a 1:1 manner. Multivariable cox proportional hazard model was used to calculate the adjusted hazard ratios (HRs) after adjustment for age, sex, and all comorbidities. Results The risk of AF in pneumoconiosis patients was 1.30‐fold higher than that of controls (95% CI = 1.17‐1.44) was the key finding. Conclusions Pneumoconiosis is associated with increased risk of incident AF.