Open AccessClinical and echocardiographic parameters as risk factors for atrial fibrillation in patients with hypertrophic cardiomyopathy
Author(s) -
Klopotowski Mariusz,
Kwapiszewska Aleksandra,
Kukula Krzysztof,
Jamiolkowski Jacek,
Dabrowski Maciej,
Derejko Pawel,
Oreziak Artur,
Baranowski Rafal,
Spiewak Mateusz,
Marczak Magdalena,
Klisiewicz Anna,
Szepietowska Barbara,
Chmielak Zbigniew,
Witkowski Adam
Publication year - 2018
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.23050
Subject(s) - medicine , hypertrophic cardiomyopathy , presyncope , cardiology , atrial fibrillation , ejection fraction , complication , cardiomyopathy , ventricular tachycardia , heart failure , heart rate , blood pressure
Background Atrial fibrillation (AF) is a common complication in patients with hypertrophic cardiomyopathy (HCM) and may contribute to high cardiovascular morbidity and mortality. Therefore, it is important to assess parameters associated with AF in HCM patients. Hypothesis The aim of the study was to evaluate AF prevalence in patients with HCM and to investigate risk factors for AF. Methods Five hundred and forty‐six HCM patients aged below 65 were included into analysis. Clinical and echocardiographic parameters were analyzed. Results In 141 patients (25.8%) AF episodes were recorded. The following factors were identified as risk factors for AF in patients with HCM: age ≥ 45 years (OR 2.38, CI 1.40‐4.05, P = 0.001), past history of presyncope or syncope (OR 2.25, CI 1.35‐3.74, P = 0.002), non‐sustained ventricular tachycardia (nsVT) (OR 2.70, CI 1.60‐4.57, P < 0.001), left atrium diameter during first assessment (OR 1.065, CI 1.03‐1.11, P = 0.001), left atrium diameter at the last assessment before AF occurrence (OR 1.10, CI 1.06‐1.14, P < 0.001) and left ventricular ejection fraction at the last assessment before AF occurrence (CI 0.96, CI 0.94‐0.98, P = 0.001). Conclusions We confirm that AF is a common complication for patients with HCM. Identification of patients with high risk for AF and implementation of preventive strategies may reduce AF occurrence and its complications.