Open AccessAssessment of Short‐term Blood Pressure Variability in Patients With Ascending Aortic Dilatation
Author(s) -
Karataş Mehmet Baran,
İpek Göktürk,
Çanga Yiğit,
Güngör Barış,
Özcan Kazim Serhan,
Arugaslan Emre,
Günaydin Zeki Yüksel,
Durmuş Gündüz,
Onuk Tolga,
Kalenderoğlu Koray,
Akdeniz Evliya,
Bolca Osman
Publication year - 2015
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.22485
Subject(s) - medicine , blood pressure , cardiology , ascending aorta , ambulatory blood pressure , diastole , ambulatory , aorta , aortic pressure
Background Blood pressure variability ( BPV ) is a novel parameter related to adverse cardiovascular findings and events, especially in hypertensive patients. The aim of the present study was to investigate the relationship between short‐term BPV and ascending aortic dilatation ( AAD ). Hypothesis Hypertensive patients with AAD may exhibit higher short‐term BPV compared to hypertensive patients with normal diameter ascending aorta and BPV may be correlated with aortic sizes. Methods Seventy‐six hypertensive patients with AAD and 181 hypertensive patients with a normal‐diameter ascending aorta were retrospectively enrolled in the study. Clinical data, echocardiographic characteristics, and 24‐hour ambulatory blood pressure monitoring characteristics were compared between the 2 groups. Standard deviation ( SD ) and Δ of BP were used as parameters of BPV . Results Although 24‐hour mean systolic blood pressure ( SBP ) and diastolic blood pressure ( DBP ) were similar between the 2 groups, the SD of SBP and SD of DBP values were significantly higher in AAD patients (17.2 ± 6.8 vs 13.8 ± 3.5, P < 0.01; and 12.1 ± 5.1 vs 10.7 ± 3.1, P = 0.02, respectively). Daytime SD of SBP values were higher in AAD patients, whereas nighttime SD of SBP values did not differ between groups. In multivariate linear regression analysis, 24‐hour SD of SBP , 24‐hour Δ SBP , daytime SD of SBP , daytime Δ SBP , and left ventricular mass index were independently correlated with aortic size index. Conclusions Our study revealed higher levels of short‐term BPV in hypertensive patients with AAD . This conclusion warrants further study.