Open AccessRanolazine in Cardiac Arrhythmia
Author(s) -
Saad Marwan,
Mahmoud Ahmed,
Elgendy Islam Y,
Richard Conti C.
Publication year - 2016
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.22476
Subject(s) - ranolazine , medicine , atrial fibrillation , cardiology , angina , cardiac arrhythmia , management of atrial fibrillation , ventricular fibrillation , intensive care medicine , myocardial infarction
Ranolazine utilization in the management of refractory angina has been established by multiple randomized clinical studies. However, there is growing evidence showing an evolving role in the field of cardiac arrhythmias. Multiple experimental and clinical studies have evaluated the role of ranolazine in prevention and management of atrial fibrillation, with ongoing studies on its role in ventricular arrhythmias. In this review, we will discuss the pharmacological, experimental, and clinical evidence behind ranolazine use in the management of various cardiac arrhythmias.