Open AccessAcute Heart Failure: Acute Cardiorenal Syndrome and Role of Aggressive Decongestion
Author(s) -
Hanna Elias B.,
Hanna Deschamps Eliana
Publication year - 2014
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.22337
Subject(s) - medicine , cardiorenal syndrome , diuretic , heart failure , acute decompensated heart failure , inotrope , cardiology , acute kidney injury , renal function , acute coronary syndrome , intensive care medicine , myocardial infarction
Congestion and acute renal dysfunction are at the center of acute heart failure ( HF ) syndromes. Acute cardiorenal syndrome, which refers to worsening of renal function in a patient with acute HF syndrome, is partly related to venous congestion and high renal afterload. Aggressive decongestion improves renal and myocardial flow and ventricular loading conditions, potentially resulting in reduced HF progression, rehospitalization, and mortality. High‐dose diuretic therapy remains the mainstay therapy. Ultrafiltration and inotropic therapy are useful in the subgroup of patients with a low‐output state and diuretic resistance.