Open AccessEtiology of Syncope in Patients Hospitalized With Syncope and Predictors of Mortality and Rehospitalization for Syncope at 27‐Month Follow‐Up
Author(s) -
Sule Sachin,
Palaniswamy Chandrasekar,
Aronow Wilbert S.,
Ahn Chul,
Peterson Stephen J.,
Adapa Sreedhar,
Mudambi Lakshmi
Publication year - 2011
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.20872
Subject(s) - medicine , syncope (phonology) , hazard ratio , atrial fibrillation , etiology , odds ratio , confidence interval , diabetes mellitus , cardiology , proportional hazards model , logistic regression , stepwise regression , endocrinology
The authors investigated the etiologies of syncope and risk factors for mortality and rehospitalization for syncope at 27‐month follow‐up in 325 consecutive patients, mean age 66 years, hospitalized for syncope. The causes of syncope were diagnosed in 241 patients (74%). Of 325 patients, 13 (4%) were rehospitalized for syncope and 38 (12%) died. Stepwise logistic regression analysis showed that significant independent prognostic factors for rehospitalization for syncope were diabetes (odds ratio [OR], 5.7; 95% confidence interval [CI], 1.6–20.4), atrial fibrillation (OR, 4.0; 95% CI, 1.0–15.6), and smoking (OR, 4.6; 95% CI, 1.3–16.8). Stepwise Cox regression analysis showed that significant independent prognostic factors for time to mortality were diabetes (hazard ratio [HR], 2.7; 95% CI, 1.4–5.2), coronary artery bypass graft surgery (HR, 2.9; 95% CI, 1.3–6.5), malignancy history (HR, 2.5; 95% CI, 1.2–5.2), narcotics use (HR, 4.0; 95% CI, 1.7–9.8), smoking (HR, 2.8; 95% CI, 1.4–5.5), atrial fibrillation (HR, 2.4; 95% CI, 1.0–5.4), and volume depletion (HR, 2.8; 95% CI, 1.4–5.8). Copyright © 2011 Wiley Periodicals, Inc. The authors have no funding, financial relationships, or conflicts of interest to disclose.