Open AccessCorrelation Study of Pulmonary Embolism and High‐density Lipoprotein Cholesterol
Author(s) -
Wang YuPeng,
Wang Ping,
Li HongWei
Publication year - 2010
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.20692
Subject(s) - medicine , pulmonary embolism , cardiology , trunk , embolism , thrombosis , deep vein , cholesterol , ecology , biology
Background It is currently thought that pulmonary embolism and deep vein thrombosis are different manifestations of the same pathological process of venous thromboembolism. Venous thromboembolism has a negative correlation with high‐density lipoprotein cholesterol. Hypothesis Pulmonary embolism has a negative correlation with the level of high‐density lipoprotein cholesterol. Methods A total of 90 patients with pulmonary embolism, diagnosed and treated at a single center, were retrospectively analyzed for the present study. Among them were 57 cases of pulmonary arterial trunk embolism in group A and 33 cases of pulmonary arterial non‐trunk embolism in group B. Results The results showed that the level of high‐density lipoprotein cholesterol decreased markedly in patients with pulmonary arterial trunk embolism as compared to those with pulmonary arterial non‐trunk embolism. A stepwise logistic regression analysis was performed upon the relationship between pulmonary arterial trunk embolism and multiple factors. The results showed that a pulmonary arterial trunk embolism had a negative correlation with the level of high‐density lipoprotein cholesterol and a positive correlation with triglyceride and high sensitivity C‐reactive protein. Conclusions Pulmonary arterial trunk embolism is negatively correlated with the level of high‐density lipoprotein cholesterol. Copyright © 2010 Wiley Periodicals, Inc.