Open AccessSleep Disordered Breathing is Associated with Appropriate Implantable Cardioverter Defibrillator Therapy in Congestive Heart Failure Patients
Author(s) -
Tomaello Luca,
Zanolla Luisa,
Vassanelli Corrado,
LoCascio Vincenzo,
Ferrari Marcello
Publication year - 2010
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.20602
Subject(s) - medicine , heart failure , cardiology , ejection fraction , implantable cardioverter defibrillator , polysomnography , central sleep apnea , sleep apnea , apnea–hypopnea index , population , sleep disordered breathing , breathing , apnea , obstructive sleep apnea , anesthesia , environmental health
Background Implantable cardioverter defibrillators (ICDs) are increasingly employed in patients affected by congestive heart failure (CHF) and sleep disordered breathing (SDB) is frequent in this population. Hypothesis To investigate SDB prevalence and influence on appropriate ICD discharges in CHF patients. Methods A total of 22 consecutive ICD patients with systolic CHF (left ventricular ejection fraction [LVEF]< 45%) were studied by polysomnography. Results A total of 17 (77.2%) showed SDB (apnea‐hypopnea index [AHI]_ 10 events/hour). After controlling for LVEF and New York Heart Association (NYHA) class, AHI and severity of hypoxia during sleep results correlated to appropriate ICD discharges ( r = 0.718; P < .001, r = − 0.619; P = .003, respectively). Conclusions Sleep disordered breathing is frequent in ICD recipients due to left systolic ventricular dysfunction and may increase the risk of ventricular arrhythmia and appropriate ICD discharges. Copyright © 2010 Wiley Periodicals, Inc.