Open AccessNonapical Tako‐tsubo Cardiomyopathy Associated with Coronary Slow Flow: A Case Report and Review of the Literature
Author(s) -
Krishnan Unni,
Zacharzewski Amanda,
Schmitt Matthias
Publication year - 2009
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.20467
Subject(s) - medicine , cardiomyopathy , cardiology , pathophysiology , coronary angiogram , radiology , coronary angiography , heart failure , myocardial infarction
The exact pathophysiology of tako‐tsubo cardiomyopathy (TTC) is unclear. A nonapical form of TTC precipitated by emotional stress is presented. Findings on 12 lead ECG and coronary angiogram are discussed. The role of specialized investigations such as cardiac MRI and tissue Doppler imaging are reviewed. We then examine the probable molecular explanations for this condition and suggest a probable molecular mechanism based on animal studies. Future therapeutic options are also briefly discussed. Copyright © 2009 Wiley Periodicals, Inc.