Open AccessClinical Efficiency and Safety Analysis of Transcatheter Closure of Multiple Atrial Septal Defects in Adults
Author(s) -
Song ZhiYuan,
He GuoXiang,
Shu MaoQin,
Hu HouYuan,
Tong ShiFei,
Ran BoLi,
Liu JianPing,
Li YongHua,
Jing Tao
Publication year - 2009
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.20450
Subject(s) - medicine , closure (psychology) , cardiology , cardiac catheterization , heart septal defect , surgery , market economy , economics
Background Transcatheter closure of atrial septal defects (ASDs) is currently a reliable alternative to surgery, even though challenging in patients with multiple ASDs. Hypothesis The aim of this study was to evaluate the clinical efficiency and safety of transcatheter closure in multiple ASDs. Methods Multiple ASDs were diagnosed by transthoracic echocardiography (TTE) or transesophageal echocardiography (TEE). The occlusive condition and distance between 2 adjacent ASDs were measured by TTE examination. Then, the number and size of the occluder(s) was determined. TTE examinations were performed after transcatheter closure as follow‐up. Results The transcatheter procedure was successful in 15 patients with multiple ASDs, using a single occluder in 9 patients and 2 occluders in the remaining 6 patients. Overall, 21 ASD occluders were implanted. During a follow‐up period of 6 mo to 5 y, a slight residual shunt was found in 1 patient without any symptoms; a moderate residual shunt was identified at the inferior vena cava and the occluder was removed by surgery 1 mo after procedure. Other complications, including endocarditis, arrhythmia, thromboembolism, and atrioventricular valve damage were not recorded in any of the 15 patients during the follow‐up period. Conclusion Transcatheter closure of multiple ASDs is safe and efficient. Two occluders are necessary for the distance of 2 ASDs more than 7 mm, and a single occluder is sufficient for those 7 mm or less. Copyright © 2009 Wiley Periodicals, Inc.