Open AccessAssessing the Current Role of Platelet Function Testing
Author(s) -
Braunwald Eugene,
Angiolillo Dominick,
Bates Eric,
Berger Peter B.,
Bhatt Deepak,
Can Christopher P.,
Furman Mark I.,
Gurbel Paul,
Michelson Alan D.,
Peterson Eric,
Wiviott Stephen
Publication year - 2008
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.20361
Subject(s) - medicine , clopidogrel , aspirin , clinical trial , intensive care medicine , platelet , clinical practice , physical therapy
In vitro platelet function tests are commonly applied in research and offer justification for using antiplatelet therapy. However, studies assessing the ability of standardized platelet function tests to predict patients' clinical response to aspirin or clopidogrel have generated contradictory results. At this time, there is no standardized definition for resistance to antiplatelet therapy, and the appropriate treatment of patients who are hyporesponsive to these agents is not known. Although such tests have a role in research, their place in guiding therapy remains to be established, and prospective trials are urgently needed. The ideal platelet function test for clinical practice would be rapid, easy‐to‐use, inexpensive, and reliable. Copyright © 2008 Wiley Periodicals, Inc.