Open AccessPaclitaxel‐induced ST‐Segment Elevations
Author(s) -
Gemici Gökmen,
Çinçin Altuǧ,
Deǧertekin Muzaffer,
Oktay Ahmet
Publication year - 2009
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.20291
Subject(s) - medicine , premedication , st segment , paclitaxel , chest pain , normal sinus rhythm , cardiology , chemotherapy , anesthesia , sinus rhythm , electrocardiography , myocardial infarction , atrial fibrillation
A 51‐year‐old woman presented with severe chest pain minutes after starting intravenous paclitaxel as a part of the systemic chemotherapy due to ovarian carcinoma. The electrocardiogram (ECG) revealed sinus rhythm with ST‐segment elevations in inferior and anterior leads. The ST‐segment elevations resolved immediately after sublingual nitroglycerine. Cardiac troponin T and CPK MB levels remained in the normal range at repeat measurements. It was presumed that in spite of standard premedication, paclitaxel had induced acute coronary syndrome with ST‐segment elevations in this patient. Copyright © 2009 Wiley Periodicals, Inc.