Open AccessSimultaneous Doppler Tracing of the Mitral Inflow and Annular Motion Provides a Useful Means of Evaluating Left Ventricular Diastolic Function
Author(s) -
Choi JinOh,
Park Seung Woo,
Shin DaeHee,
Han Hyejin,
Cho Sungwon,
Kim Jun Hyung,
Song Young Bin,
Lee SangChol
Publication year - 2008
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.20241
Subject(s) - medicine , diastole , cardiology , diastolic function , doppler effect , receiver operating characteristic , confidence interval , doppler echocardiography , blood pressure , physics , astronomy
Background In this study, we evaluated the feasibility and clinical usefulness of TS E−E ′, the time interval between the onsets of early diastolic mitral inflow velocity (E) and mitral annular velocity (E′), obtained by simultaneously tracing E and E′, in terms of evaluating diastolic function. Methods By the diastolic functional status, 105 patients were allocated to abnormal relaxation, pseudonormal filling (PN), or normal diastolic function groups (n = 30, 43, and 32, respectively). The TS E−E ′was measured in the same cardiac cycle by the pulsed‐wave Doppler (PWD) tracing of mitral inflow near the septal annulus with appropriate filter and gain settings. Results TS E−E ′was prolonged in the PN group versus the normal group (34.1 ± 12.2 msec versus 12.1 ± 8.5 msec, p≤0.001). The area under the receiver operating characteristic curve of TS E−E ′for the detection of PN was 0.91 (95% confidence interval [CI]; 0.85 ∼ 0.97, p<0.001), and 24.0 msec was determined to be the optimal cut‐off value (specificity 83.7%, sensitivity 90.3%). Conclusion Simultaneous measurement of TS E−E ′is feasible and clinically applicable for the grading of diastolic dysfunction (DD). Copyright © 2008 Wiley Periodicals, Inc.