Open AccessDevelopment and Validation of a Noninvasive Method to Estimate Cardiac Output Using Cuff Sphygmomanometry
Author(s) -
Chio ShiuShin,
Tsai Jeffrey J.,
Hsu YenMing,
Lapointe Jeffrey C.,
HuynhCovey Thao,
Kwan Oi Ling B.,
DeMaria Anthony N.
Publication year - 2007
Publication title -
clinical cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.263
H-Index - 72
eISSN - 1932-8737
pISSN - 0160-9289
DOI - 10.1002/clc.20164
Subject(s) - medicine , dobutamine , cuff , cardiology , blood pressure , sphygmomanometer , doppler effect , hemodynamics , anesthesia , surgery , physics , astronomy
Background Obtaining cardiac output (CO) measurements noninvasively during routine blood pressure recording can improve hypertension management. A new method has been developed that estimates cardiac output using pulse‐waveform analysis (PWA) from a brachial cuff sphygmomanometer. This study evaluates the ability of PWA to track changes in CO as derived by Doppler ultrasound during dobutamine stimulation. Hypothesis This study aims to validate the PWA CO estimation over a wide CO range as would be obtained by dobutamine stimulation during Doppler ultrasound evaluation. Method A total of 48 patients undergoing standard dobutamine stress echocardiography testing for accepted clinical indications were enrolled. Among them, 44 patients (age 36–83, 18 females, 26 males) with good waveform data for analyses provided estimates of CO in this study. Noninvasive measurements of CO were performed using both Doppler ultrasound recordings and PWA techniques simultaneously at each stage of dobutamine infusion. Results A total of 207 simultaneous pulse‐waveform analyses and Doppler measurements were taken during dobutamine stress on 44 cardiac patients. Linear regression analysis revealed good intra‐patient correlation between pulse‐waveform analysis and Doppler at different dobutamine‐induced CO with coefficients from r = 0.69 to 0.98 ( p < 0.05). Analysis of all patients yielded an overall correlation of r = 0.82 ( p < 0.001, bias = 0.4 L/min, standard deviation = 1.8 L/min). Conclusion The CO measured noninvasively from a sphygmomanometer using this PWA method correlates well with those of Doppler through a range of dobutamine‐stimulated levels. The CO by PWA should be useful for monitoring hemodynamic changes in hypertensive and cardiac patients during routine blood pressure measurement. Copyright © 2007 Wiley Periodicals, Inc.