Premium
Semiparametric transformation models for multivariate panel count data with dependent observation process
Author(s) -
Li Ni,
Park DoHwan,
Sun Jianguo,
Kim KyungMann
Publication year - 2011
Publication title -
canadian journal of statistics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.804
H-Index - 51
eISSN - 1708-945X
pISSN - 0319-5724
DOI - 10.1002/cjs.10118
Subject(s) - multivariate statistics , covariate , semiparametric regression , inference , event (particle physics) , econometrics , computer science , estimating equations , semiparametric model , statistical inference , statistics , count data , regression analysis , transformation (genetics) , regression , mathematics , artificial intelligence , estimator , nonparametric statistics , poisson distribution , biochemistry , chemistry , gene , physics , quantum mechanics
This article discusses regression analysis of multivariate panel count data in which the observation process may contain relevant information about or be related to the underlying recurrent event processes of interest. Such data occur if a recurrent event study involves several related types of recurrent events and the observation scheme or process may be subject‐specific. For the problem, a class of semiparametric transformation models is presented, which provides a great flexibility for modelling the effects of covariates on the recurrent event processes. For estimation of regression parameters, an estimating equation‐based inference procedure is developed and the asymptotic properties of the resulting estimates are established. Also the proposed approach is evaluated by simulation studies and applied to the data arising from a skin cancer chemoprevention trial. The Canadian Journal of Statistics 39: 458–474; 2011 © 2011 Statistical Society of Canada