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Publication year - 2020
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.202090031
Subject(s) - chemistry , amination , enantioselective synthesis , intramolecular force , methylene , cover (algebra) , surface modification , combinatorial chemistry , simple (philosophy) , stereochemistry , catalysis , medicinal chemistry , organic chemistry , mechanical engineering , engineering , philosophy , epistemology
The inside cover picture shows a simple and efficient method for the synthesis of chiral β‐lactams via Pd(II)‐catalyzed intramolecular enantioselective amination of methylene C(sp 3 )−H bonds. The magical combination of 2‐pyridinylisopropyl (PIP) auxiliary and 3,3’‐substituted BINOL‐type ligands proves to be a general solution for the asymmetric functionalization of unbiased methylene C(sp 3 )−H bonds. More details are discussed by Shi et al . on page 242 — 246.

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