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Radical Carbonylation under Low CO Pressure: Synthesis of Esters from Activated Alkylamines at Transition Metal‐Free Conditions
Author(s) -
Zhao Fengqian,
Ai HanJun,
Wu XiaoFeng
Publication year - 2021
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.202000624
Subject(s) - chemistry , carbonylation , transition metal , catalysis , phenols , metal , organic chemistry , functional group , carbon monoxide , polymer
Main observation and conclusion High CO pressure (> 40 bar) is usually needed in radical carbonylation reactions in the absence of metal catalyst. In this communication, we developed a transition‐metal‐free radical carbonylation of activated alkylamines with phenols and alcohols under low CO pressure (1—6 bar). Various esters were obtained in moderate to excellent yields under simple reaction conditions with good functional group compatibility.