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Pd‐Catalyzed Transfer of Difluorocarbene for Three Component Cross‐Coupling †
Author(s) -
Xu ZhiWei,
Zhang Wei,
Lin JinHong,
Jin ChuanMing,
Xiao JiChang
Publication year - 2020
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.202000297
Subject(s) - difluorocarbene , catalysis , coupling (piping) , chemistry , aryl , component (thermodynamics) , physics , medicinal chemistry , materials science , organic chemistry , thermodynamics , alkyl , metallurgy
Summary of main observation and conclusion Outstanding accomplishments have been achieved in the chemistry of difluorocarbene, but transition‐ metal‐catalyzed transfer of difluorocarbene for coupling remains a challenging task. Herein, we describe a Pd‐catalyzed coupling of difluorocarbene with two aryl carbon centers to give difluoromethylenation products, which cannot be obtained by any previous difluorocarbene‐transformation method.