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Synthesis of N ‐Heterocyclic Carbine Silver(I) and Palladium( II ) Complexes with Acylated Piperazine Linker and Catalytic Activity in Three Types of C—C Coupling Reactions
Author(s) -
Liu Qingxiang,
Zhang Xiantao,
Zhao Zhixiang,
Li Xinying,
Zhang Wei
Publication year - 2021
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.202000237
Subject(s) - chemistry , piperazine , sonogashira coupling , catalysis , palladium , linker , denticity , medicinal chemistry , carbene , stereochemistry , organic chemistry , polymer chemistry , crystal structure , computer science , operating system
Main observation and conclusion Two bis‐imidazolium salts LH 2 ·Cl 2 and LH 2 ·(PF 6 ) 2 with acylated piperazine linker and two N ‐heterocyclic carbene (NHC) silver(I) and palladium(II) complexes [L 2 Ag 2 ](PF 6 ) 2 (1) and [L 2 Pd 2 Cl 4 ] (2) were prepared. The crystal structures of LH 2 ·Cl 2 and 1 were confirmed by X‐ray analysis. In 1, one 26‐membered macrometallocycle was generated through two silver(I) ions and two bidentate ligands L. The catalytic activity of 2 was investigated in Sonogashira, Heck‐Mizoroki and Suzuki‐Miyaura reactions. The results displayed that these C—C coupling reactions can be smoothly carried out under the catalysis of 2.