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Cover Picture: Highly Regioselective Sequential 1,1‐Dihydrosilylation of Terminal Aliphatic Alkynes with Primary Silanes (Chin. J. Chem. 5/2019)
Author(s) -
Cheng Zhaoyang,
Xing Shipei,
Guo Jun,
Cheng Biao,
Hu LanFang,
Zhang XingHong,
Lu Zhan
Publication year - 2019
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201990051
Subject(s) - regioselectivity , chemistry , silanes , acetylene , catalysis , chin , rare earth , cover (algebra) , combinatorial chemistry , organic chemistry , mineralogy , medicine , mechanical engineering , silane , engineering , anatomy
The cover picture shows that sequential 1,1‐dihydrosilylation of terminal aliphatic alkynes with primary silanes enabled by one earth‐abundant cobalt catalyst has been developed. This protocol is operationally simple using readily available aliphatic alkynes, including simple acetylene and complex drug derivative, for efficient access to valuable gem‐bis(dihydrosilyl)alkanes in highly regioselective and atom‐economic manners. Corresponding asymmetric transformations are achieved with excellent enantioselectivities. More details are discussed in the article by Lu et al . on page 457–461.