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Inside Cover: Biomimetic Chiral Pyridoxal and Pyridoxamine Catalysts (Chin. J. Chem. 2/2019)
Author(s) -
Chen Jianfeng,
Liu Yong Ethan,
Gong Xing,
Shi Limin,
Zhao Baoguo
Publication year - 2019
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201990022
Subject(s) - chemistry , pyridoxamine , transamination , pyridoxal , catalysis , cover (algebra) , vitamin b6 , amino acid , organic chemistry , combinatorial chemistry , stereochemistry , enzyme , vitamin , biochemistry , mechanical engineering , engineering
The inside cover picture shows the development of chiral pyridoxal and pyridoxamine catalysts by mimicking vitamin B 6 ‐dependent enzymes. These chiral pyridoxals and pyridoxamines displayed extraordinary catalytic performances in asymmetric biomimetic transamination and Mannich reaction, to give various chiral α‐amino acids and α,β‐diamino acid esters in good yields with excellent diastero‐ and/or enantioselectivities. The research has provided some useful information for further applications of the catalytic power of vitamin B6 in the area of asymmetric cayalysis. More details are discussed in the article by Zhao et al. on page 103–112.