Copper‐Catalyzed Benzylic C—H Functionalization, Oxidation and Cyclization of Methylarenes: Direct Access to 2‐Arylbenzothiazoles | Zendy

Yu Wentao | Zendy; Wu Wanqing | Zendy; Jiang Huanfeng | Zendy

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Copper‐Catalyzed Benzylic C—H Functionalization, Oxidation and Cyclization of Methylarenes: Direct Access to 2‐Arylbenzothiazoles

Author(s) -

Yu Wentao,

Wu Wanqing,

Jiang Huanfeng

Publication year - 2019

Publication title -

chinese journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.28

H-Index - 41

eISSN - 1614-7065

pISSN - 1001-604X

DOI - 10.1002/cjoc.201900340

Subject(s) - chemistry , surface modification , catalysis , copper , sulfide , potassium , medicinal chemistry , combinatorial chemistry , organic chemistry

Summary of main observation conclusion The direct C—H functionalization of methylarenes is of great significance. Herein, a copper‐catalyzed oxidative C—N/C—S bond formation through benzylic C(sp 3 )—H functionalization, oxidation and cyclization of methylarenes is reported. Various 2‐arylbenzothiazoles have been synthesized in moderate to excellent yields with readily available o ‐iodoaniline, potassium sulfide, and methylarenes as raw materials.

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