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Electrochemical Radical Borylation of Aryl Iodides
Author(s) -
Hong Junting,
Liu Qianyi,
Li Feng,
Bai Guangcan,
Liu Guoquan,
Li Man,
Nayal Onkar S.,
Fu Xuefeng,
Mo Fanyang
Publication year - 2019
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201900001
Subject(s) - chemistry , borylation , aryl , aryl radical , electrochemistry , combinatorial chemistry , catalysis , radical , functional group , photochemistry , organic chemistry , electrode , alkyl , polymer
Summary of main observation and conclusion Herein, we report the first electrochemical strategy for the borylation of aryl iodides via a radical pathway using current as a driving force. A mild reaction condition allows an assorted range of readily available aryl iodides to be proficiently converted into synthetically valuable arylboronic esters under transition metal catalyst‐free conditions. Moreover, this method also shows good functional group tolerance. Initial control mechanistic experiments reveal the formation of aryl radical as a key intermediate and the current plays an important role in the generation of radical intermediate.