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Cover Picture: Visible Light Accelerated Vinyl C–H Arylation in Pd‐Catalysis: Application in the Synthesis of ortho Tetra‐substituted Vinylarene Atropisomers (Chin. J. Chem. 1/2018)
Author(s) -
Feng Jia,
Li Bin,
Jiang Julong,
Zhang Mingkai,
Ouyang Wenbai,
Li Chunyu,
Fu Yao,
Gu Zhenhua
Publication year - 2018
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201880011
Subject(s) - chemistry , atropisomer , palladium , tetra , photochemistry , catalysis , visible spectrum , kinetic isotope effect , chin , cleavage (geology) , kinetic energy , medicinal chemistry , stereochemistry , organic chemistry , deuterium , physics , optoelectronics , quantum mechanics , medicine , geotechnical engineering , fracture (geology) , engineering , anatomy
The cover picture shows a protocol of a palladium‐catalyzed arylation of vinylarenes with diaryliodonium salts with the assistance of visible light. A palladium‐vinylarene complex may be excited via the visible light irradiation, where the kinetic isotope effect ( k H / k D ) was around 1.1. However under darkness, the reaction proceeded very slowly, and the kinetic isotope was found as 3.6, indicating the C—H bond cleavage step is the rate‐determining step. This protocol avoided high reaction temperature and enabled us to access a series of ortho tetra‐substituted vinylarene atropisomers with high enantiospecificity. More details are discussed in the article by Gu et al. on page 11–14.